General Info:

In clinical studies, people treated with XENICAL and a reduced-calorie diet with no more than 30% of calories from fat achieved significantly greater weight loss than people who were treated with diet alone.

Unlike other commonly prescribed weight-loss medications, XENICAL is not an appetite suppressant and does not have a direct effect on the brain. Instead, it works in your digestive system to block about one-third of the fat in the food you eat from being digested.

Because XENICAL interferes with your body's absorption of some fat-soluble vitamins, you should take a daily multivitamin supplement that contains vitamins D, E and K and beta carotene once a day at least 2 hours before or after taking XENICAL, such as at bedtime.

Typically, people begin losing weight within 2 weeks of starting XENICAL, and may continue to lose weight for 6 to 12 months, at which point weight loss usually begins to level off - even if you're still taking XENICAL. This doesn't mean that XENICAL is not working. People who continue to take XENICAL are better able to maintain their weight loss.